Merck’s Covid Drug Not Effective At Preventing Household Transmission
Merck and Co's late-stage trials failed to show that its oral antiviral Lagevrio, also known as molnupiravir, cut the risk of preventing covid from spreading to others living in the same house. Merck had hoped to build a case for use of the medication as prophylactic treatment.
Reuters:
Merck's COVID Pill Fails To Prevent Infection Among Household Members
Merck & Co Inc said on Tuesday its COVID-19 pill was not effective at cutting the risk of coronavirus infections in people living with someone infected with the virus. The results were similar to data from rival Pfizer Inc, whose COVID pill Paxlovid also failed to prevent infections among household contacts. (2/21)
FiercePharma:
Slump Of Merck's COVID-19 Pill Continues With Trial Failure
Initially hyped as a game-changing COVID-19 treatment, the shine was off Merck and Ridgeback’s oral antiviral Lagevrio (molnupiravir) even before it was authorized for use in the United States. Nevertheless, the pill generated more than $6.6 billion in sales over its first five quarters on the market, despite mounting evidence of its limited effectiveness. (Dunleavy, 2/21)
From the states —
Des Moines Register:
Tyson Foods’ Petition In COVID Death Cases Dismissed By Supreme Court
The U.S. Supreme Court has declined to hear Tyson Foods’ arguments about why federal judges should oversee lawsuits tied to the COVID-19 deaths of workers at its plants, including its nearly 2,800-worker pork processing plant in Waterloo. The court on Tuesday denied Tyson’s petition to review the decision of lower court judges, who ruled in multiple cases that Tyson employees can sue the company in state-level courts. (Jett, 2/21)
USA Today:
Idaho Bill Could Criminalize Anyone Administering MRNA COVID Vaccines
Two Republican Idaho lawmakers last week introduced a new bill that would criminalize the administration of mRNA vaccines across the state. ... Under the bill, all mRNA technology would be banned in the state.If passed, the Idaho state code would be amended so that those administering mRNA vaccines to any person or mammal within the state would face misdemeanor charges. (Nguyen, 2/21)
KHN:
California Says It Can No Longer Afford Aid For Covid Testing, Vaccinations For Migrants
All day and sometimes into the night, buses and vans pull up to three state-funded medical screening centers near California’s southern border with Mexico. Federal immigration officers unload migrants predominantly from Brazil, Cuba, Colombia, and Peru, most of whom await asylum hearings in the United States. (Thompson, 2/22)
In other covid-related research —
Scientific American:
COVID Poses Severe Risks During Pregnancy, Especially In Unvaccinated People
Millions of people have been pregnant and given birth during the pandemic. When the COVID-causing virus SARS-CoV-2 first emerged, it wasn’t clear what additional risks—if any—it posed to pregnant people and their babies. But accumulating evidence now shows that having COVID during pregnancy increases the likelihood of severe outcomes and death in the parent, as well as the possibility of fetal complications. (Lewis, 2/22)
Ars Technica:
Unvaccinated More Likely To Have Heart Attack, Stroke After COVID, Study Finds
A bout of COVID-19 is known to increase a person's long-term risks of having a major cardiovascular event, such as a heart attack or stroke. But being fully vaccinated or even partially vaccinated appears to bring that risk down, according to a study published this week in the Journal of the American College of Cardiology. (Mole, 2/21)
Los Angeles Times:
Kids Under 5 Being Left Behind With COVID-19 Vaccines
Black and Latino children in Los Angeles County younger than 5 have COVID-19 vaccination rates in the single digits, reflecting a broad trend nationwide that has public health experts concerned and seeking ways to boost those figures. Only 12% of children between 6 months and 4 years old have received at least one dose of a COVID-19 vaccine, and only 7% are fully vaccinated, according to L.A. County data. (Evans, 2/21)
CIDRAP:
CIDRAP Unveils Roadmap For Advancing Better Coronavirus Vaccines
Before the COVID-19 pandemic, the warning signs for newly emerging and deadly coronaviruses were already flashing bright red. Researchers were still working on SARS-CoV studies in 2012 when the even deadlier MERS-CoV arrived on the scene in the Middle East, repeatedly jumping from camels over the years and sparking large healthcare-related outbreaks. (Schnirring, 2/21)
Meanwhile, the pandemic is having unexpected side-effects —
Fox News:
Post-COVID, Many Parents Are Giving Kids Fever-Reducing Medicine When It's Not Necessary: Study
Parents might want to think twice before reaching for aspirin or ibuprofen to bring down a child’s fever. One in three parents give their kids fever-reducing medicine when it’s not really needed, a new study from Michigan Medicine at the University of Michigan found. (Rudy, 2/21)
