Stick To Full Two-Dose Vaccine Regimen, FDA Tells Health Officials
Ideas like cutting dosages in half or skipping the second shot have been floated to accelerate U.S. distribution of the covid vaccine. But FDA officials says that deviating from the tested and approved protocols could undermine the vaccination efforts.
NPR:
FDA Warns Health Officials Not To Mess With COVID-19 Vaccine Doses Schedule
The U.S. Food and Drug Administration is warning health care workers that any changes to the authorized dosing schedules of COVID-19 vaccines currently being administered significantly place public health at risk and undermine "the historic vaccination effort to protect the population" from the coronavirus pandemic. The first and second doses of the Pfizer-BioNTech vaccine are approved to be delivered within a 21-day window, while the Moderna injections should be spread over 28 days. When given at those intervals, both vaccines are about 95% effective, according to the respective drugmakers. But the FDA has heard suggestions that the number of limited doses could be stretched by cutting them in half, extending the length of time between doses, or mixing and matching vaccines in order to immunize more people against COVID-19. (Romo, 1/4)
CNN:
FDA Says People Need Both Doses Of Coronavirus Vaccines
Anyone who receives the Moderna or Pfizer vaccine must get two full doses, two top US Food and Drug Administration officials said Monday. They also dismissed other ideas for stretching the vaccine supply and said people who are speculating about the possibility of making do with just one dose or cutting doses in half are misinterpreting the data. (Fox, 1/4)
The Washington Post:
U.S. Health Officials Say They Plan To Stick With Two-Dose Coronavirus Regimen
The U.S. government’s top infectious-disease doctor, a leading drug regulator and the Health and Human Services secretary are dismissing suggestions that the second shot of authorized coronavirus vaccines could be delayed to make more doses available faster to more people. In recent days, some public health experts have debated whether it is worth taking a scientific gamble by altering the two-dose regimen that proved highly effective in trials to maximize the number of people partially protected with at least one shot as the pandemic surges. (Johnson, 1/4)
Bloomberg:
FDA Sends Rebuke To Officials Seeking To Alter Vaccine Regimen
Moncef Slaoui, chief scientific officer of Operation Warp Speed, the U.S. government’s vaccine drive, asked Moderna and the FDA to cut in half the dose of the company’s vaccination for people 18 to 55 after finding evidence that it induces the same immune response. That would double the amount of vaccine available for the age group, while providing the same level of protection, he said on CBS’s “Face the Nation” on Sunday. Meanwhile, a U.K. plan would allow for second doses of vaccines to be administered as many as 12 weeks after the first, longer than the timing determined as optimal for shots developed by Pfizer Inc. and Moderna. (1/5)
