Houston-based Legacy Community Health Services, a federally qualified health center, is trying hard to fight the Zika virus. It’s screening pregnant women and following federal guidelines to test people at risk.
But despite best efforts, there’s a problem, says Legacy’s chief medical officer, Dr. Ann Barnes. Women who could be infected usually have to wait as long as a month to know if their pregnancy is at risk. That’s the turnaround time from the state public health lab, where blood samples are sent for testing.
“In that situation, the anxiety a pregnant woman has to live with is great,” Barnes said. “Ideally, we’d be able to speed up the process.”
It’s not just an issue in Houston. In areas where Zika poses a threat, public health departments are struggling to meet the need to test patients for the mosquito-borne virus, even for those the government has classified as “at risk.”
Doctors and health experts say last month’s approval of $1.1 billion in emergency funding by Congress — a spending package to fight the virus — could help, giving local labs the resources to efficiently determine if people have been infected.
Federal health officials this week gave a rough outline of how this funding will be distributed.
Specifically, Congress directed $394 million to the Centers for Disease Control and Prevention, the bulk of which will support state and local Zika response efforts such as mosquito control and emergency response teams, public education campaigns, efforts to improve diagnostic tests, and research to track how the virus affects children long-term. That includes money for expanding lab capacity — though it is yet unclear exactly how much of those resources will be used for this activity. The U.S. Department of Health and Human Services, which includes the CDC, has until the end of October to craft a spending plan.
“These funds will hopefully allow the infrastructure for testing to be expanded,” said Andrew Pekosz, a professor of microbiology at Johns Hopkins University’s Bloomberg School of Public Health.
Zika is already spreading in Florida. The CDC has recommended that pregnant women in particular get tested, since the virus can cause birth defects and other complications. About 80 percent of infected people don’t show symptoms, so a test is the only way to know if they have contracted Zika.
“Especially for a pregnant woman, getting an answer quickly is a big deal,” said Dr. Jesse Goodman, a professor of medicine and infectious diseases at Georgetown University Medical Center in Washington, D.C. “You’re going to be very concerned. If that concern can be reduced, that’s going to be good for you.”
But the additional federal funding will not be an immediate fix.
Given how long processing and budgeting can take, public health labs aren’t expecting the cash infusion until early 2017, said Peter Kyriacopoulos, senior director of public policy at the Association of Public Health Laboratories.
While the congressional funding is a promising start, more investment is necessary, added Chris Gould, senior director for federal government relations at the Association of State and Territorial Health Officials. Local health departments have been shrinking over the past six years. Many don’t have the staffs large enough to operate labs at the level needed, given the volume of samples coming in. They need to expand manpower, especially since testing for Zika isn’t their only responsibility, he said.
Kyriacopoulos estimates that labs would need about $39 million to adequately meet these challenges. And public health experts expect the virus to return next summer, he said, which could create a need for further funding down the line.
Meanwhile, the CDC has already tried to alleviate some lab strain. Last month, it purchased $2.5 million worth of diagnostic supplies for states offering lab testing. And labs have been working on their own to try to expand capacity — especially ones serving areas such as Florida, Texas and California, where the warmer, mosquito-friendly climate heightens the risk that Zika could spread.
But still, local health departments offering Zika testing remain “understaffed and overwhelmed,” said Dr. Martha Rac, a maternal-fetal medicine specialist at Texas Children’s Pavilion for Women and Baylor College of Medicine, in Houston.
The burden doesn’t fall evenly, she noted. In urban centers such as Houston, women who may have been infected are more likely to get a Zika test than are those from a poorer, rural town in south Texas. There, the public health clinics or lab systems may not be as well-resourced, so women have fewer options.
“We’re not there yet when it comes to turnaround and capacity,” said Dr. Umair Shah, executive director of the public health department in Texas’ Harris County, which encompasses Houston. The backlog, he said, makes it harder for women in particular to get the medical counsel they need in an appropriate timeframe.
Predicting future need is also tricky. Even now, states have been encouraging pregnant women to get tested, along with men who may have been exposed and are showing the virus’ flu-like symptoms. But that leaves out other groups, such as asymptomatic men who may have contracted Zika and could pass it on to female partners. If states start to push for that testing as well, it could exacerbate lab strain.
Plus, it’s difficult to gauge whether demand will dip in the coming months. Technically, mosquito season peaks in the summer. But in high-risk states like Florida or Texas, the insects carrying Zika can persist into December and even January, Shah said.
Beyond sheer lab capacity, HHS is also planning to invest some of its new Zika funding into developing better tests to detect the virus. Currently, labs use one test to detect the virus within two weeks of exposure, and another that will find it for up to three months. But the second test — which is more commonly used — is less precise and can, for instance, detect false positives if someone’s been exposed to other, similar diseases.
The federal government intends to use some of its funding to support trials for new, better diagnostics. That investment is crucial, Rac said, especially given the magnitude of threat Zika still poses.
“There’s still a lot we need to know we need to figure out,” she said. “And who knows what’s going to happen? … This mosquito’s pretty resilient to destruction. This is something we’re going to see for some time.”
