The Washington Post: New CDC Chief Stepped Down From Four Groups To Comply With Ethics Rules
Centers for Disease Control and Prevention Director Robert Redfield has resigned his  positions at four groups, including a gene therapy biotechnology company and a conservative AIDS organization, to comply with government ethics rules, according to his financial disclosures. Redfield, a longtime HIV/AIDS researcher who started the job March 26, succeeded Brenda Fitzgerald, the former Georgia public health commissioner, who resigned Jan. 31 after serving only half a year because she was unable to divest from her financial holdings. She had also purchased tobacco stocks as CDC director. (Sun, 4/17)

The Wall Street Journal: New CDC Chief Resigned From Four Entities To Comply With Ethics Rules
In a Public Financial Disclosure Report, memorandum and letter reviewed by the Journal, Dr. Redfield, a veteran HIV/AIDS researcher, said he had resigned as a professor of medicine and from other posts at the University of Maryland. His compensation from the beginning of 2017 through March 2018 was $757,100 plus a $70,000 bonus. The CDC director’s compensation is $375,000. Dr. Redfield also resigned as consultant and chair of a clinical advisory committee for American Gene Technologies International Inc., a gene therapy biotech company; as a director of Children’s AIDS Fund International, an AIDS service organization with faith-based roots; and as a medical consultant for Guidepoint Global LLC, an advisory firm. He sold his stock in American Gene Technologies International and sold stock and forfeited options in Profectus Biosciences Inc., a vaccine development company. (McKay, 4/17)

In other administration news —

The Hill: HHS Chief Azar Postpones Appearance At Hearing 
Health and Human Services Secretary Alex Azar is postponing a planned appearance before a Senate committee on Thursday as he recovers from an intestinal condition, an HHS official said Tuesday. The official said Azar, who was hospitalized overnight on Sunday before being released, has had his first bout of diverticulitis, an infection of pouches in the colon that can be painful. (Sullivan, 4/17)

Stat: Bernie Sanders Bill Would Impose Jail Time For Execs Behind Opioid Crisis
Sen. Bernie Sanders (I-Vt.) will introduce a bill Tuesday that would impose jail time for pharmaceutical executives whose companies engage in manipulative practices when marketing opioids. The legislation would impose a 10-year minimum prison sentence and fines equal to an executive’s compensation package if the individual’s company is found to have illegally contributed to the opioid crisis. It would also impose an additional fine on those companies of $7.8 billion — one-tenth the annual cost of the crisis, per a 2016 estimate. (Facher, 4/17)

The Hill: Sanders Unveils Bill Targeting Drug Companies Over Opioid Crisis
The bill bans companies from marketing opioids to consumers as nonaddictive, and fines them 25 percent of profits from opioid products if they are found in violation. “They knew how dangerous these products were but refused to tell doctors and patients,” he said. “Yet, while some of these companies have made billions each year in profits, not one of them has been held fully accountable for its role in an epidemic that is killing tens of thousands of Americans every year.” (Sullivan, 4/17)

In other news on the opioid crisis from Capitol Hill —

The Hill: House Panel To Mark Up Opioid Bills Next Week
A House Energy and Commerce subcommittee will mark up legislation next Wednesday aimed at combatting the opioid epidemic. The April 25 markup in the panel’s health subcommittee comes as the panel's chairman pushes forward with his target of bringing a bill to the House floor by Memorial Day weekend. So far, lawmakers have reviewed more than 60 bills over three legislative hearings. (Roubein, 4/18)

Health News Florida: Congressman Announces Plan To Address Opioid Crisis
U.S. Rep. Vern Buchanan announced an anti-drug plan Monday to address the growing opioid crisis. According to the Manatee County Republican, the bill will be introduced in the U.S. House later this week. The Opioid Emergency Response Act, is a seven-point plan built around ideas already introduced in Congress that adds incentives to use alternatives to addictive prescription opioids. (Martin, 4/17)

The Hill: GOP N.H. Governor Confronted White House Over Lack Of Opioid Funding: Report 
GOP New Hampshire Gov. Chris Sununu initially resisted a visit to his state from President Trump last month over the country's opioid addiction crisis, telling the White House that he didn't want his state used as a prop for the administration. CBS News reports  that Sununu battled White House aide Katy Talento, who sits on the White House Domestic Policy Council, over whether Trump could come to the state to promote his plan to battle the opioid epidemic while not providing additional funding for state initiatives. (Bowden, 4/17)

The Associated Press: Citing Opioid Crisis, Feds Seek Rule Change For Drugmakers
Drugmakers would be required to identify a legitimate need for controlled substances to justify their production under a proposed rule change intended to rein in the diversion of drugs for illicit purposes, the Drug Enforcement Administration announced Tuesday. According to the DEA, current regulations were issued in 1971 but need to be updated to reflect the nation’s opioid abuse crisis and changes in the manufacture of controlled substances. (Raby, 4/17)

The Wall Street Journal: U.S. Proposes Quota Changes For Drug Enforcement Administration
Attorney General Jeff Sessions announced the publishing of the proposed rule changes in a speech in North Carolina, saying the action would help address the nation’s opioid problem, which he called “the deadliest drug crisis in American history.” Under the proposal, the Drug Enforcement Administration must consider how much drugs, particularly powerful opioid painkillers, are being misused, abused or causing overdoses when setting production quotas. The DEA will be required to assess information provided by government health agencies such as the Federal Drug Administration, as well as the states. (Wilber, 4/17)

The Hill: DEA Moves To Curb Oversupply Of Opioids 
“Under this proposed new rule, if DEA believes that a company’s opioids are being diverted for misuse, then they will reduce the amount of opioids that company can make,” Attorney General Jeff Sessions said Tuesday during remarks he gave on the opioid crisis in North Carolina. (Roubein, 4/17)

Politico: Patrick Kennedy Profits From Opioid-Addiction Firms
Patrick Kennedy, the former Democratic representative and scion of the liberal political dynasty, has emerged as the unlikely go-to player for companies seeking to benefit from the Trump administration’s multibillion-dollar response to the opioid crisis, reaping well over $1 million in salaries and equity stakes in the firms. The 50-year-old son of the late Sen. Edward M. Kennedy, who stepped down from Congress in 2011 amid his own decades-long battles with addiction and mental illness, is a high-profile mental health advocate who sat on President Donald Trump’s opioid commission. (Cancryn, 4/17)

The Associated Press: Dozens Arrested In Drug Bust In Huntington, West Virginia
Dozens of people were arrested Tuesday in a major drug trafficking sweep in Huntington, West Virginia, a city hit hard by the opioid epidemic. U.S. Attorney Mike Stuart said more than 200 federal, state and local law enforcement officers targeted nearly 100 people for arrests aimed at dismantling a multi-state distribution network. He said 30 arrests were made as of midday Tuesday in the state’s second-largest city. (Raby, 4/17)

Boston Globe: Push Is On To Refresh State Fund That Helps Municipalities Buy The Anti-Opioid Narcan
There’s a new push to replenish the state fund designed to cut the cost of the life-saving drug naloxone, months after its financial backing quietly dried up, increasing the price local first responders pay by nearly twofold. Attorney General Maura Healey’s office confirmed Tuesday that it deposited $250,000 last week into the Municipal Naloxone Bulk Purchase Trust Fund, providing the account with its first fresh infusion since it was depleted last fall. (Stout, 4/17)

Denver Post: Pledging To Punish The “Poison Pushers” In Colorado, A New Partnership Forms To Fight Heroin
A coalition of Colorado law enforcement and health care providers said Tuesday that it will punish the “poison pushers” who spread heroin and fentanyl, and it will offer a helping hand to Colorado’s many addicts. Heroin distributors and dealers need to know cops are coming for them with the full backing of the federal government, said U.S. Attorney Bob Troyer. But the newly formed Heroin Impact Project goes beyond the typical law enforcement focus on drug dealers. This time, they will be offering support to those who are struggling with addiction, he said. (Phillips, 4/17)

Health News Florida: Miami Sues Drug Makers Over Opioid Epidemic
In 2016, the city of Miami saw 641 opioid-related overdoses, a 20 percent increase from the year before. Now, attorneys for the city have filed a lawsuit in Miami-Dade County circuit court alleging that drug manufacturers violated Florida law by aggressively and deceptively marketing opioids as safe. The 134-page suit filed Monday alleges that the drug-manufacturing industry worked to cultivate a narrative “that pain was undertreated,” which paved the way for increased prescribing of opioids for chronic pain. (4/17)

The Baltimore Sun: Hospital Emergency Rooms In Maryland Struggle With Flood Of Patients With Mental Health, Substance-Use Issues
Emergency room physicians and hospital officials in Maryland say they have become overwhelmed with such patients in need of treatment for mental health or substance-use problems. Emergency room visits in Maryland fell 8 percent from 2013 to 2016, but the number of patients with behavioral health problems jumped 18.5 percent. Such cases now make up roughly a quarter of all emergency visits in Maryland. (Cohn and McDaniels, 4/18)

Milwaukee Journal Sentinel: How Medication Can Treat Opioid Addiction
As the U.S. continues to grapple with a deadly opioid epidemic, a top health official in the Trump administration says all options should be on the table for addiction treatment — including medication. “It takes a culture change,” said Elinore McCance-Katz, a physician and assistant secretary of mental health and substance abuse for the U.S. Department of Health and Human Services. (Luthern, 4/17)

The Associated Press: Dem Senator: Trump VA Pick Vows Not To Privatize Vets Care
President Donald Trump's pick to be Veterans Affairs secretary is promising not to privatize the agency, a key Democratic senator said Tuesday, taking a stance on a politically charged issue that his predecessor says led to his firing. The confirmation hearing of Ronny Jackson, Trump's White House doctor and a Navy rear admiral chosen to speed up improvements to the VA, is scheduled for next week. On Tuesday, he met privately with Sen. Jon Tester of Montana, the top Democrat on the Senate Veterans Affairs Committee, as a part of visits this week to assure lawmakers he could effectively lead the government's second-largest department. (Yen, 4/17)

The Hill: Trump's VA Pick Pledges Opposition To Privatization, Senator Says
Sen. Jon Tester (Mont.), the ranking Democrat on the Senate Veterans’ Affairs Committee, said Jackson pledged during a one-on-one meeting that he is against privatization. “He said all the right things, seems to have the same position on privatization that Shulkin had,” Tester told reporters. “He answered the questions right on privatization.” Political tensions about privatization could complicate the confirmation process. (Weixel, 4/17)

In other news —

The New York Times: An Army Veteran Confronts His Own Trauma With A Camera
It was a cold, sunny day last spring when retired U.S. Army Specialist Michael McCoy visited the war memorial in Cumberland, Md., to look for the name of Pfc. Albert M. Nelson. Mr. McCoy, who grew up in West Baltimore, and Mr. Nelson, who was from West Philadelphia, became close friends in 2006 just before Mr. McCoy’s second of two yearlong deployments to Iraq. Mr. Nelson was a bit of a joker and, at 31, a few years older than the other soldiers. He was a big brother figure, well liked, especially by Mr. McCoy. (O'Reilly, 4/18)

The Wall Street Journal: UnitedHealth Increases Guidance For Year
UnitedHealth Group Inc. posted a 31% increase in profit for its latest quarter and raised its earnings outlook for the year. UnitedHealth, the parent of the biggest U.S. health insurer, on Tuesday reported a first-quarter profit of $2.84 billion, or $2.87 a share, up from $2.17 billion, or $2.23 a share, a year earlier. The company earned $3.04 a share on an adjusted basis, compared with $2.37 a share. (Prang, 4/17)

Modern Healthcare: UnitedHealth's First-Quarter Revenue Climbs As Medicare Advantage Membership Grows 
As health insurance companies continue to evolve from their traditional role as claims processors to care facilitators and blur the lines between payer and provider, UnitedHealth leads the pack. Other insurers are playing catch-up. The insurer has been adding doctor practices and lower-cost outpatient facilities to its portfolio of businesses in a bid to better control where patients access care. Most recently, its Optum subsidiary in December said it would buy DaVita's medical group, which boasts 300 medical clinics, along with 35 urgent-care centers and six outpatient surgery centers. The insurer also picked up Surgical Care Affiliates, an operator of ambulatory surgery centers, and MedExpress, an operator of urgent-care clinics, in recent years. (Livingston, 4/17)

The Star Tribune: UnitedHealth Group Hikes Outlook After Quarterly Profit Easily Beats Estimates
During a conference call Tuesday to discuss first-quarter results, Renfro said the venture fund will invest in a variety of emerging health care technologies including digital care, consumer care and health analytics with artificial intelligence, big data and machine learning. "A tremendous effort will go into ventures," Renfro said. "We hope to accelerate early-stage, open-market innovations across the breadth of the health care services marketplace, with up to $600 million in newly committed funds." (Snowbeck, 4/17)

Stat: Bezos Has Invested In Direct Primary Care. Could It Be In Amazon's Future?
It’s the stuff disruptors dream of. A group of Seattle doctors and investors had a plan to revolutionize primary care by freeing themselves, and their patients, from the dictates of insurance. They would charge a monthly membership fee for delivering on-demand medical services. No insurance bureaucracy. No reimbursement delays. No incomprehensible bills. In 2010, Amazon founder Jeff Bezos became one of the project’s biggest investors, providing an infusion of capital and the instant credibility his name conveys. The company, called Qliance (pronounced Key-liance), scored early successes in Seattle but faltered amid a series of financial setbacks. It closed its doors last summer. (Ross, 4/18)

In other health industry news —

Reuters: Ford Expands U.S. Medical Ride Business Built Around Its Vans
Ford Motor Co said on Wednesday that it was expanding a medical transport service called GoRide in Southeast Michigan, one of several efforts by the U.S. automaker to build new ride service businesses around its Transit commercial van. Under a multi-year agreement with Michigan healthcare system Beaumont Health, Ford will use Transit vans to transport patients to medical appointments, or from hospitals to home or rehabilitation centers. (White, 4/18)

The Washington Post: 1 In 4 New York City Mice Carry Drug-Resistant Bacteria, Study Finds
Potentially harmful germs dwell inside the guts of urban mice, according to a team of scientists who trapped more than 400 of the rodents around New York City. The researchers, conducting the largest survey of microorganisms living in city mice, also identified several genes that give germs resistance to antibiotic drugs. “This doesn't tell us that these mice are directly responsible for infecting humans,” said W. Ian Lipkin, director of Columbia University's Center for Infection and Immunity. “But they have the potential to do so.” (Guarino, 4/17)

The Wall Street Journal: Mice In New York Carry Rare And Dangerous Diseases, Study Finds
In addition, the mice carried 36 types of viruses, most of which had never before been seen in mice. Mice found in the Manhattan neighborhood of Chelsea, which were fatter than other mice, harbored the greatest number of viruses. The results were published in the journal mBio. The precise level of dangerousness of New York City mice feces was, until now, not fully researched. The findings, in part, confirm common sense: Mouse droppings really are stomach-churning. For the immunosuppressed, ill or very old, mice with pathogenic microbes can be especially dangerous. (West, 4/17)

NPR: Mouse Droppings Carry Human Disease Bacteria
"You not only have mice carrying bacteria that have the potential to cause human disease, but also carrying bacteria that have components that actually would thwart our ability to treat these infections with antibiotics," (Dr. Ian) Lipkin says. Lipkin stresses that the researchers haven't actually linked mice to any large outbreaks of human disease. So people shouldn't overreact whenever they see a mouse in the house. But they should take steps to protect themselves. (Stein, 4/17)

Stat: Scientists Find Antibiotic-Resistance Genes In Germs Carried By NYC Mice
Just because certain bacteria are present does not suggest they are going to be pathogenic — meaning they can first infiltrate our systems and then cause disease, said Timothy Walsh, an expert on antimicrobial resistance at Cardiff University, who was not involved with the study. Past research has found similar bacterial warning signs in mice in other parts of the world, but they haven’t led to outbreaks of human disease. (Joseph, 4/17)

The Washington Post: Ethicist Foresees Choosing Your Baby From Dozens Of Embryos
So you want to have a baby. Would you like a dark-haired girl with a high risk of someday getting colon cancer, but a good chance of above-average music ability? Or would you prefer a girl with a good prospect for high SAT scores and a good shot at being athletic, but who also is likely to run an above-average risk of bipolar disorder and lupus as an adult? (Ritter, 4/18)

Los Angeles Times: Attention Women: Your Choice Of Blood Pressure Medicine May Affect Your Risk Of Pancreatic Cancer
In findings with potentially broad implications for the public's health, new research has found that some women who treat their high blood pressure with a class of drugs that relaxes the blood vessels were more likely to develop pancreatic cancer than those who use other hypertension medications. In a large and intensively-studied group of middle-aged and older women, the risk of developing pancreatic cancer was more than twice as high for those who took a short-acting calcium channel blocker for more than three years. (Healy, 4/17)

NPR: Exercise Is Best Bet Against Falls
Falls are a leading cause of injury and death among older adults. In 2014, about 1 in 3 adults aged 65 and older reported falling, and falls were linked to 33,000 deaths. If you want to reduce the risk of falling, regular exercise may be your best bet, according to the latest recommendations from the U.S. Preventive Services Task Force. The influential group came to that conclusion after reviewing evidence from about 20 studies that included adults 65 and older. (Aubrey, 4/17)

The New York Times: Nuts May Be Good For The Heart, But Are Hardly A Miracle Food
There is considerable research showing that nuts, with their high levels of unsaturated fatty acids, fiber and minerals, may help reduce the risk for cardiovascular disease. But a large Swedish analysis published in Heart has found that the benefits are limited and depend largely on other healthy behaviors. Researchers followed 61,364 adults for up to 17 years. They had all completed questionnaires on diet, lifestyle and other risk factors for chronic disease. (Bakalar, 4/17)

The Washington Post: Face Transplant: Frenchman Jerome Hamon Is World’s First To Have It Done Twice
Jérôme Hamon is the first person in the world to receive two face transplants. And a few months after receiving his second transplant in January, he spoke to reporters and told them that he was feeling well. “I still have moments when I’m exhausted, but overall I feel well,” he said. (Rosenberg, 4/17)

Kaiser Health News: Drug Test Spurs Frank Talk Between Hypertension Patients And Doctors
There’s an irony at the heart of the treatment of high blood pressure. The malady itself often has no symptoms, yet the medicines to treat it — and to prevent a stroke or heart attack later — can make people feel crummy. “It’s not that you don’t want to take it, because you know it’s going to help you. But it’s the getting used to it,” said Sharon Fulson, a customer service representative from Nashville, Tenn., who is trying to monitor and control her hypertension. (Farmer, 4/18)

Stat: WHO Ruling Could Put Fate Of Sanofi's Dengue Vaccine On The Line
There’s a lot on the line this week for Sanofi Pasteur’s troubled dengue vaccine, Dengvaxia. On Wednesday, an expert panel that advises the World Health Organization will vote to update its recommendations outlining how and when the vaccine should be used — and more importantly, how and when it should not be administered. A decision is expected Thursday. (Branswell, 4/17)

Sacramento Bee: UC Davis Medical Students Hold Protest After Stephon Clark Shooting
Lying on the cement in front of the University of California, Davis School of Medicine in Sacramento, roughly 100 medical students participated in a "die-in" protest Tuesday, urging healthcare providers to do more to help people experiencing trauma after police incidents. Tuesday's event was hosted by the school's chapter of White Coats 4 Black Lives, a national group founded in 2015 in the aftermath of the police shooting of Michael Brown and the in-custody death of Eric Garner. (Chavez, 4/17)

The Associated Press: Bills To Curtail LGBT Rights Are Failing In US Legislatures
In a striking shift from recent years, major legislation curtailing LGBT rights has been completely stymied in state capitols around the country this year amid anxiety by Republican leaders over igniting economic backlash if they are depicted as discriminatory. In the thick of this year's legislative sessions, LGBT activists were tracking about 120 proposed bills that they viewed as threats to their civil rights. Not one of them has been enacted as many sessions now wind down; only two remain under serious consideration. (4/17)

The Cleveland Plain Dealer: Ohio Legislators Look To Clamp Down Harder On Communities That Try To Pass Local Gun Restrictions
Ohio lawmakers blocked cities and villages from enacting their own gun laws 12 years ago, but now they want to remove any wiggle room that could allow new restrictions and penalties in local communities. Language inserted months ago into a "stand your ground" bill is getting new attention from city leaders who want to pass gun laws in the wake of shootings in Parkland, Florida, and Las Vegas. (Borchardt, 4/17)

KCUR: State Of Kansas Takes Control Of 15 Financially Troubled Private Nursing Homes 
The owner and operator of 15 Kansas nursing homes has consented to be placed in receivership after defaulting on payments to vendors and failing to meet payroll. Kansas Department for Aging and Disability Services Secretary Tim Keck has been appointed receiver and will oversee operations of the homes, which are scattered across the state. The owner, Skyline Health Care LLC of Wood-Ridge, New Jersey, previously acknowledged that it had insufficient funds to pay basic utilities and food service vendors. (Margolies, 4/17)

Boston Globe: Mass. Is About To Become A Battleground Over Transgender Rights
In the campaign video, the little girl wearing ponytails and Mary Janes looks bewildered. There’s a man beside her at the sink in a public restroom. He’s putting on lip gloss. “A little girl shouldn’t have to wonder why there’s a man using the women’s bathroom,” says the child narrator. Expect many similar images this year as Massachusetts becomes ground zero in the latest round of the nation’s culture wars. A November ballot question asking voters whether to keep or repeal the state’s 2016 antidiscrimination law is expected to be the first statewide referendum on transgender rights, taking the national temperature on a fiery hot social issue. (Ebbert, 4/17)

Georgia Health News: Facing Heat From Governor, Blue Cross And Piedmont Settle Dispute
The pressure from Gov. Nathan Deal evidently worked. Deal announced Tuesday afternoon that Blue Cross and Blue Shield of Georgia and Piedmont Healthcare had reached a “handshake” agreement on a new contract. The accord thus met his deadline of close of business Tuesday, after which the state would have been forced, in his words, “to initiate executive action.” (Miller, 4/17)

The Associated Press: Advocates Call For Action On State's Maternal Mortality Rate
Women's reproductive health advocates are calling on New York officials to take steps to reduce the state's maternal mortality rate among black women. Planned Parenthood of New York leaders, state Assembly members and maternity health services providers held a news conference in Albany Monday to call for action to reduce the state's national ranking of 30 out of 50 states when it comes to maternal deaths. (4/17)

KCUR: Overland Park Weight-Loss Hospital Sues After Government Cuts Off Medicare Funding 
An Overland Park hospital that specializes in weight-loss surgery is suing government health officials after they cut off its participation in Medicare. Blue Valley Hospital (BVH), an acute care facility at 129th Street and Metcalf Avenue, claims to perform 35 percent of all Missouri Medicaid bariatric surgeries, the umbrella term for weight-loss operations. If it loses its Medicare funding and has to shut down, “the residents of Kansas and Missouri will lose access to crucial bariatric procedures, which are necessary to prevent a multitude of life-threatening and life-altering conditions,” the suit alleges. (Margolies, 4/17)

Health News Florida: Senators Back Hospitals On Payment Challenges
Tampa General Hospital is throwing its support behind a bipartisan proposal that, if passed by Congress, would allow it and other large health-care systems to challenge how the government estimates additional Medicare payments. U.S. Sen. Marco Rubio, R-Fla., and U.S. Sen. Bill Nelson, D-Fla., are filing legislation Tuesday that would strike a provision in current law that precludes hospitals from challenging such payment decisions or the data used in reaching the decisions. (4/17)

California Healthline: California Insurer Faces Whistleblower Complaint Over Health Law Taxes
A federal whistleblower complaint alleges that a major California insurer failed to pay an estimated $89 million in taxes on premium revenue as required under the Affordable Care Act. The complaint against Blue Shield of California focuses on the taxation of certain health plans that are funded by both an employer and insurer. It could spark more scrutiny by federal officials into whether all insurers are paying their fair share of taxes on premiums. (Terhune, 4/17)

Seattle Times: Washington Spends Little To Help The State’s 900,000 Smokers Quit — Despite Collecting $622M In Tobacco Taxes 
Nearly 8,300 Washingtonians die from tobacco-related illness each year: more than car crashes, suicide, opioid overdoses and alcohol combined. And smoking costs Washington an estimated $2.8 billion per year in direct medical costs, including almost $790 million in Medicaid spending. Yet, with nearly 900,000 smokers in the state and $622 million in tobacco-related tax collections, Washington spends almost no money on programs to help people quit. (Alexander, 4/17)

The Associated Press: N.H. Child Advocate Asks For Greater Authority To Protect Kids
New Hampshire's new child advocate is pressing for changes to the law to strengthen her office's ability to protect the state's most vulnerable residents. Lawmakers created the office last year as part of larger effort to reform New Hampshire's Division of Children, Youth and Families, which has been under scrutiny since two toddlers under its supervision were killed in 2014 and 2015. (4/17)

The Associated Press: Florida Lawyer Gets Prison For Role In $23M Insurance Fraud
A Florida man has been sentenced to more than a year in prison for his role in a $23 million auto insurance fraud involving chiropractors' clinics. The SunSentinel reports 55-year-old Jason Dalley wept in court Monday as a judge sentenced him to spend a year and nine months in prison and pay more than $1.8 million in restitution. (4/17)

The Washington Post: E. Coli Romaine Lettuce Contamination: New Jersey Woman Sues Panera Bread
A 66-year-old woman who was sickened by E. coli is suing Panera Bread after apparently eating contaminated romaine lettuce at a restaurant in New Jersey. Louise Fraser first experienced abdominal pain within days of eating at a restaurant in Somerset County, according to a federal complaint. Then came bloody diarrhea and vomiting that sent her to the emergency room March 25. Doctors diagnosed hemolytic uremic syndrome, a life-threatening illness that happens to a small number of people infected with Escherichia coli and can lead to kidney failure. (Phillips, 4/17)

Sacramento Bee: Water Along The Lower American River In Sacramento Shows High Levels Of E. Coli, According To New Weekly Testing
Water at one of Sacramento’s most popular public beaches regularly records E. coli levels far higher than what federal regulators recommend as safe for recreational use. Tiscornia Beach, at the confluence of the American and Sacramento rivers near Discovery Park, recorded E. coli levels in February that were seven times the threshold set by the Environmental Protection Agency, according to new weekly testing by the Central Valley Regional Water Quality Control Board. (Fletcher, 4/17)

KPCC: 'It's Nowhere Near Enough': LA Homeless Advocates React To Mayor's Shelter Plan
Los Angeles Mayor Eric Garcetti has a new plan to try to solve the city's homeless crisis. Garcetti would like to spread temporary shelters across the city, placing one in each of L.A.'s 15 council districts. There's also a promise of more enforcement to keep the areas near those shelters clear of homeless encampments. It's an ambitious plan with a $20 million price tag. Andy Bales is CEO of the Union Rescue Mission. The mayor's proposal is a good first step, Bales said, but more needs to be done. (Henderson, 4/16)

The Wall Street Journal: Italy Serves Cautionary Lesson For New Trump Drug Plan
The Trump administration is pushing drug plans that tie costs to performance as a way to lower health-care spending in the U.S. In Italy—where they’ve used the strategy for years—such plans haven’t brought down costs. A number of global drug companies, in response to criticism of high prices in the U.S., have recently committed to tying the cost of some of their most-expensive treatments to how well they work. So called “outcomes-based” contracts—which reimburse insurance companies for treatments that turn out to be ineffective—has been trumpeted by the industry as a way to lower health-care costs, while also avoiding broad price cuts. (Bisserbe, 4/17)

Axios: Pharma's Biggest Concern Is A Trump Surprise
President Trump is scheduled to give a speech on drug prices next week, but few expect the policy proposals that will accompany it to pack a real punch to the pharmaceutical industry — unless the president goes off-script. What they're saying: “We are hopeful the administration will embrace market-oriented policies that address patient affordability ... We would obviously be concerned if the administration pursued Medicare negotiation or importation which we think would take the system in the wrong direction," said Stephen Ubl, president and CEO of the Pharmaceutical Research and Manufacturers of America. (Owens, 4/16)

Reuters: As Cancer Drug Prices Climb, Value Not Keeping Pace
The cost of new anti-cancer drugs increased more than five-fold from 2006 to 2015, but a new analysis suggests that cancer patients and insurers may be getting less for their money. Anticancer medications account for the lion’s share of global drug spending, and the average price per month of these drugs is known to have more than doubled in recent years, Dr. Kelvin Chan of Sunnybrook Health Sciences Centre in Toronto and colleagues note in the Journal of Oncology Practice. (4/12)

Bloomberg: Coke Versus Pepsi Of Drugmakers? Wall Street Doesn't Buy It 
Hours after markets closed on Bristol-Myers Squibb Co.’s worst day in more than a year, executives used a sugary analogy to explain to Wall Street why the drugmaker’s new cancer treatment would do just fine against its main competitor. “Point blank, these are Coke and Pepsi in lung cancer, OK?” Bristol-Myers Chief Scientific Officer Thomas Lynch told a hotel ballroom packed with analysts and investors at a major medical conference in Chicago. Merck & Co.’s drug, Keytruda, had shown impressive results at the conference -- but Bristol-Myers was right there with it, Lynch said. (Hopkins and Lipschultz, 4/17)

The Wall Street Journal: Why Merck Is Betting Big On One Cancer Drug
Merck & Co. is making one of the biggest bets on a single drug in the pharmaceutical industry, a move that is risky but that could, if successful, pay off for the company and a broad array of cancer patients. Merck’s Keytruda, a new type of cancer drug that harnesses patients’ immune systems to fight tumors, is already marketed to treat lung, skin, bladder and other cancers. Global sales soared to more than $3.8 billion in 2017—about 9% of Merck’s total revenue—fueled by a monthly U.S. price tag of $13,500 and studies showing it prolongs patient survival in some cancers. (Loftus, 4/15)

Stat: Will A $300 Hep C Treatment Break Gilead's Grip On Mid-Income Countries?
With an eye toward making a low-cost hepatitis C treatment available in numerous countries, a nonprofit says that a mid-stage study showed an experimental combination of two pills appeared safe and effective, while offering high cure rates for hard-to-treat patients. The results were greeted with enthusiasm by patient advocacy groups, because once testing is completed, the nonprofit hopes to register the combination treatment in middle-income countries, starting with Malaysia, where it could be sold for $300, or about half the price of existing treatment in that country. (Silverman, 4/12)

Kaiser Health News: Federal Appeals Court Puts Chill On Maryland Law To Fight Drug Price-Gouging
States continue to battle budget-busting prices of prescription drugs. But a federal court decision could limit the weapons available to them — underscoring the challenge states face as they, in the absence of federal action, go one-on-one against the powerful drug industry. The 2-to-1 ruling Friday by the U.S. 4th Circuit Court of Appeals invalidated a Maryland law meant to limit “price-gouging” by makers of generic drugs. The measure was inspired by cases such as that of former Turing Pharmaceutical CEO Martin Shkreli, who raised one generic’s price 5,000 percent after buying the company. (Luthra, 4/17)

Modern Healthcare: Highmark Health Strikes Outcomes-Based Contract For Asthma Drug 
Highmark Health, a Pittsburgh-based Blues plan, has entered into a value-based drug-pricing contract with pharmaceutical company AstraZeneca for Symbicort, which is used to treat asthma and other chronic lung diseases. Under the contract, Highmark said it will track whether the symptoms of its plan members using Symbicort are in line with the results of AstraZeneca's clinical trials. If the drug doesn't live up to its promise, AstraZeneca will provide Highmark with some savings. Highmark didn't release specifics on the agreement's financial terms, but said the contract applies to commercial members in Pennsylvania, West Virginia and Delaware. (Livingston, 4/17)

Stat: How Well Do Biotech And Pharma Pay? A Breakdown By Company 
Using data from MyLogIQ, which collects data from filings from the Securities and Exchange Commission, we charted the median salaries for 32 biopharma companies, ranging from the tiny Geron to the multinational Johnson & Johnson. The result: The drug business pays better than any other industry, according to MyLogIQ. (Garde, 4/16)

The Hill: New Affordable Drugs Advocacy Group Pledges Six Figures In First 2018 Endorsement
A new drug-pricing advocacy group on Tuesday announced its first endorsement of the 2018 campaign, backing Rep. David McKinley (R-W.Va.) for standing up to pharmaceutical companies. The group, Patients for Affordable Drugs NOW, which was founded this year, says it will spend six figures on the race and is seeking to help counterbalance pharmaceutical companies’ spending in November's midterm elections. (Sullivan, 4/17)

Stat: Trade Secrets Battle Between Alnylam, Dicerna Is Just One Of Many
Douglas Fambrough III had good news about his fledgling biotech company when he met with a roomful of investment analysts in a swanky midtown Manhattan hotel on a November morning in 2014. During a half-hour presentation at the Lotte New York Palace, the chief executive of Dicerna Pharmaceuticals Inc. showed 19 slides that gave an overview of his Watertown, Mass., firm. The 11th one featured a diagram with circles and squiggly lines. It represented a new delivery system for gene-silencing drugs that Dicerna hoped to develop to treat rare disorders. (Saltzman, 4/17)

Stat: A Digital Medicine Firm Tries To Adopt Pharma's Patent Game. Will It Work?
In biopharma, patents are everything. In tech? Not so much. Which is why it was unusual to see a company that’s trying to turn software into medicine announce this week that it’s bagged several patents. Boston-based Akili Interactive Labs’s new patents, issued in the U.S. and Japan, are meant to deter competitors from copying the algorithms underlying the video games it’s developing to try to treat conditions like ADHD, depression, and multiple sclerosis. (Robbins, 4/13)

Stat: U.S. Catching Up To Europe On Biosimilars, FDA Official Insists
The Food and Drug Administration lags behind its European counterpart when it comes to approving biosimilars — but a top agency official insisted Tuesday that the agency is not as far behind as some critics suggest. Leah Christl, the associate director for therapeutic biologics at the FDA’s Center for Drug Evaluation and Research, pushed back on an oft-cited statistic that shows the European Medicines Agency has so far approved more than 40 biosimilars, drugs that are almost identical to biologics, compared to just nine approved in the U.S. by the FDA. (Mershon, 4/17)

The Wall Street Journal: Johnson & Johnson Raises Sales Outlook
Johnson & Johnson reported higher-than-expected sales in its latest quarter and boosted its sales outlook for the year despite ongoing pricing pressures for its prescription drugs and medical devices. J&J said it planned to cut costs in its supply chain by $600 million to $800 million a year by 2022. To carry out the changes, J&J expects it will take $1.9 billion to $2.3 billion in charges over the next several years. (Rockoff, 4/17)

Stat: FDA Takes How Long To Warn Companies About Plant Problems? 
For companies readying medicines for regulatory approval, the Food and Drug Administration can take up to half a year to issue follow-up warning letters over problematic manufacturing facilities. Last year, the median time it took the agency to issue a warning letter was 191 days, or slightly more than six months after closing an inspection and sending a so-called 483 form to a drug maker, according to a report released by the FDA. (Silverman, 4/17)

Bloomberg: Sanofi To Sell Generics For $2.4 Billion To Focus On Biotech
Sale adds to Brandicourt’s transactions to overhaul SanofiSanofi plans to sell its European generic-drug unit to buyout firm Advent International Corp. for 1.9 billion euros ($2.4 billion) as part of a broader move by Chief Executive Officer Olivier Brandicourt to focus resources on biotechnology and new medicines. Advent has made a binding and fully financed offer, and the companies are in exclusive negotiations, Paris-based Sanofi said in a statement Tuesday. The deal should close by the end of the year, it said. (Serafino and Baigorri, 4/17)

Stat: Canadian Online Pharmacy Fined $34 Million For Selling Counterfeit Meds
A Canadian online pharmacy company that figured prominently in a scandal several years ago over a counterfeit cancer medicine sold to U.S. doctors has been fined $34 million, a penalty that a nonprofit advocacy group with ties to the pharmaceutical industry called a “slap on the wrist.” Companies controlled by Canada Drugs had sold $78 million in mislabeled and unapproved medicines, including two counterfeit batches of the Avastin cancer treatment, that were made in several countries, according to federal prosecutors. The version of Avastin that was sold to U.S. doctors in 2011 did not contain any active ingredient. The brand-name medicine is marketed by Roche. (Silverman, 4/16)

Forbes: Bristol Partners With Illumina On Diagnostic Test To Use With Opdivo
Drug giant Bristol-Myers Squibb is partnering with Illumina, the leading maker of DNA sequencing gear, to develop diagnostic tests that will pair with Bristol's cancer drugs. One of the first tests will be for tumor mutation burden, a measure of how much a tumor's DNA has changed compared to the patient's healthy cells. Cancer drugs that target the immune system, like Bristol's Opdivo (2017 sales: $4.9 billion) and Yervoy (2017 sales: $1.2 billion), may work better in patients where the tumor mutation burden is higher, because this may make the cancer easier for the immune system to "see." (Herper, 4/13)

NBC Connecticut: Bill Aims To Make Drug Prices More Transparent
A new poll found that many Connecticut residents are concerned about rising drug prices, and state lawmakers are now trying to pass a bill to hold drug companies accountable. Berlin resident Greta Stifel was diagnosed with a rare cancer in 2015.“Having a chronic illness requires extensive work to find the right treatment and medical team,” she said. “The last thing I need is to figure out how to afford my medications.” (Rayner, 4/12)

Forbes: Drug Prices Are Too Expensive: Here's How Technology Can Fix That
The cost of drug development has skyrocketed, but disruptive technologies can bring it back down to earth. Over the past several decades, drug-development costs have risen significantly, from $250 million per approved drug prior to the 1990s to $403 million in the 2000s and $873 million in 2010 ($1.778 billion if capitalization over the 14-year approval period is accounted for). Costs are distributed across the development cycle, with about one-third in discovery/preclinical development, two-thirds in clinical development and 5% in submission-to-launch. (Gunjan Bhardwag, 4/16)

Bloomberg: Johnson & Johnson Earnings: Fine For Now
Johnson & Johnson is in rarefied air. The world's largest health-care company (at $348 billion in market value, topping Pfizer by more than $130 billion) on Tuesday reported quarterly earnings and revenue that beat analyst estimates -- which has become a routine -- and raised its sales forecast for the year. But for all of its strengths, the company's hefty valuation leaves it little room for error. (Max Nisen, 4/17)

The Washington Examiner: To Bring Down Prescription Prices, Trump Should Make Foreign Governments Pay More For US-Made Drugs
As President Trump seeks to lower drug prices, he should consider introducing an export price floor on foreign drug sales. That course of action would allow U.S. drug manufacturers to earn higher revenue on their foreign sales and thus offset the exorbitant prices they charge U.S. consumers. But an export price floor would also offer a moral market correction.After all, the current U.S. export market for drug sales is neither fair on U.S. consumers nor reflective of free market forces. (Tom Rogan, 4/17)

Hartford Courant: Stabilize Naloxone Prices
ver the last decade, the price of naloxone, a medication used to reverse the effects of opioids and prevent overdoses, has skyrocketed. One naloxone delivery system, Evizo, was priced at $690 in 2014 but is $4,500 today, a price increase of more than 500 percent, which makes it impossible for most Americans to access.In response, Connecticut lawmakers have proposed legislation that could help stabilize the price of this life-saving medication. (Nicholas John and Carrie Wade, 4/16)

Forbes: Novartis CEO: How To Create Cheaper Alternatives To The Most Expensive Drugs
Recently, FDA Commissioner Scott Gottlieb addressed those in attendance at America’s Health Insurance Plans’ (AHIP) National Health Policy Conference. His comments created a lot of visibility around several critical topics, including patient access to innovative treatments, cost-effectiveness, and the role that biosimilars – biologic products that are highly like already-approved and marketed medicines (called reference or originator products) – play in helping deliver access and cost-savings. A report from the Kaiser Family Foundation in 2015 found that 29 of the 50 most expensive drugs by Medicaid spending per prescription are biologics, many of which have faced no competition in the U.S. for more than a decade. (Vas Narasimhan, 4/12)

Bloomberg: Private Equity Shapes Up For A Drugs Duel In Europe
After losing out on one of the biggest leveraged buyouts in recent years, Advent International Corp. is getting its own back. The private equity firm is in exclusive talks to buy Sanofi's European generic drugs business -- almost a year after trying to land German peer Stada Arzneimittel AG and being outbid by Bain and Cinven. (Chris Hughes, 4/17)

The Washington Post: Facebook Knows A Ton About Your Health. Now They Want To Make Money Off It.
Let’s say you have had discussions on Facebook about your breast cancer diagnosis. It has been a useful forum for comparing treatment options with others who have dealt with similar health issues. There’s only one problem: Facebook has now categorized you as a patient, and you constantly receive precisely targeted ads about cancer services available near you. They are showing up on your computer screen at work, for all your co-workers to see, right when you’re up for a big promotion. Many users experience a version of this scenario when they receive creepily personalized ads while browsing on Facebook. When those ads follow users onto sites outside Facebook, it feels like an invasion of privacy. But how do you regulate data privacy in an age of big-data black boxes? (Kirsten Ostherr, 4/18)

Boston Globe: Controversy Shadows Trump’s Pick As CDC Director
The director of the Centers for Disease Control and Prevention is arguably the nation’s chief public health officer, someone who should be the trusted face of an agency that plays a critical role in everything from highway safety campaigns to Ebola and flu research. If only the Trump administration felt the same way. The White House raised eyebrows in public health circles last month when it named Dr. Robert Redfield as director of the CDC, in part because the administration seemed to overlook longstanding doubts about his research. ...Senator Patty Murray of Washington, the ranking Democrat on a key health committee, wrote a letter asking President Trump to reconsider the appointment, citing a “pattern of ethically and morally questionable behavior.” (4/18)

Stat: A Surgeon's (Unsaid) Advice: 'Sweetheart, Don't Forget Your Tourniquet'
Five years ago, my 9-year old daughter and I were approaching the finish line of the Boston Marathon when bombs exploded in two different sites. I will never forget the feelings I had as a father shielding his daughter from the surrounding chaos, a husband looking for his wife who was running the marathon, and a surgeon trying to get to the hospital to help those who were injured. Although three people died that day, nearly 300 others who were injured were saved by a combination of heroic efforts from bystanders and nearby medical and emergency personnel. First responders, both civilian and professional, used belts, apron strings, and even new clothes to control bleeding from injured limbs. At the most basic level, these pre-hospital heroes employed improvised versions of an often-overlooked device: the tourniquet. (Jeffrey Kalish, 4/16)

Stat: Making Health Research Relevant And Less Feared In The Mississippi Delta
When the Centers for Disease Control and Prevention makes maps examining the health of Americans, my state of Mississippi lights up red, as do other states in the rural South. Part of the problem is that people living here often lack the information they need to stay healthy or manage their conditions. Far too often, information that would be relevant to them just doesn’t exist. That’s because people from communities like mine in the Mississippi Delta — rural citizens, those with low incomes, and people of color — tend not to participate in health research. (Freddie White-Johnson, 4/18)

Bloomberg: Better Diets Save Lives. Government Can Help. 
The food that people eat has become a major risk factor for disability and death worldwide. Yet countries and their philanthropic supporters seem not to be paying attention. They're investing far too little in improving diets and preventing nutrition-related disease. (Jessica Fanzo, 4/17)

The Washington Post: How Is Health Care In Puerto Rico After Hurricane Maria? No One Knows. 
Last month, I traveled to Puerto Rico to get a handle on what doctors are seeing on the island now, six months after the storm. Doctors there say that poor data collection and underreporting are hiding a health crisis whose true scale eclipses official accounts. ...The problems are particularly acute for chronically ill patients. Wendy Matos, a physician who supervises nearly 470 doctors as the executive director of the University of Puerto Rico’s faculty practice plan, said that her clinics are seeing increases in cardiac arrest and intracranial hemorrhage (bleeding inside the skull), more waterborne and infectious disease and swelling numbers of suicides since Maria. (Mekela Panditharatne, 4/18)

The New York Times: We’re Bad At Evaluating Risk. How Doctors Can Help.
My patient and I were locked in a game of decision-making hot potato. “What would you do, Doc?” he said. We’d been discussing whether he should get screened for prostate cancer. Such questions trouble most doctors. We often lob the choice back to patients, or “on the one hand, on the other hand” so much they start sympathizing with Harry Truman, who jokingly wished for one-handed advisers. (Dhruv Khullar, 4/17)

Stat: Is It Ever OK For Doctors To Lie To Their Patients?
Doctors shouldn’t lie to their patients, even now when the parsing of words and the telling of white lies is common at the highest level of our government. But they do it all the time — sometimes for personal reasons but most of the time for what they believe is the good of their patients. ...But perhaps we sometimes lie for our own sake, and it is our feelings that need to be spared so we can get through the night without breaking down in the call room when all signs indicate the outcome will not be good. (Nana Matoba and Angira Patel, 4/17)

Des Moines Register: Parents Are Hesitating To Address Their Kids' Mental Health Problems
I recently paid my friend Megan Gogerty, a fellow East High School alum and playwriting instructor at the University of Iowa, a compliment on how measured and thoughtful she is — especially when she talks me through some crisis of depression or anxiety. I gushed that Megan always seemed so poised and that I admired and envied those qualities in her. Megan countered with more wisdom: "You get the greatest hits version of me. You don't see all the messy stuff behind the scenes." (Daniel P. Finney, 4/18)

Chicago Tribune: Based On Boehner's Reversal, Pot Politics Can Depend On When You Ask
For the politics of pot, the times they are a-changin’. But in which direction? For some politicians, that can depend on when you ask. For example, former House Speaker John Boehner, who was “unalterably opposed” to marijuana legalization as recently as 2015, announced on Twitter last week that he is joining the weed industry and the legalization cause. (Clarence Page, 4/17)