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Pharma&Tech072221

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Wednesday, Jul 21 2021

Analysis: Necessary or Not, Covid Booster Shots Are Probably on the Horizon

Elisabeth Rosenthal

In today’s pharmaceutical universe, a simple “safe and effective” determination by the Food and Drug Administration to approve a drug can be manipulated to sell products of questionable value. And drugmakers can profit handsomely.

New Research Finds J&J Vaccine Has Muscle Against Covid’s Delta Variant

Victoria Knight

The data is reassuring to people who got this shot.

Novavax’s Effort to Vaccinate the World, From Zero to Not Quite Warp Speed

Sarah Jane Tribble and Rachana Pradhan

Novavax is a vaccine company that, despite $2 billion in new federal and international funding, still hasn't come through with a licensed covid vaccine. It hopes it can still help to fight the global covid scourge, but will it deliver?

Fútbol, Flags and Fun: Getting Creative to Reach Unvaccinated Latinos in Colorado

John Daley, Colorado Public Radio

A vaccine clinic came to an international soccer tournament in Denver recently. It was an attempt to reach Latino Coloradans, whose vaccination rates trail those of non-Hispanic whites.

Most Inmates Have Had Their Covid Shots — But Their Guards Likely Haven’t

Amy Worden

Hesitancy about the vaccines among prison staffers has led to a striking disparity: Inmates are better protected than corrections officials.

As Covid Vaccinations Slow, Parts of the US Remain Far Behind 70% Goal

Martha Bebinger, WBUR and Blake Farmer, Nashville Public Radio

Vermont and Massachusetts lead the nation, with more than 70% of adults having had at least one dose of a covid-19 vaccine. Southern states like Tennessee lag far behind.

Without Enough Boots on the Ground, California’s Vaccination Efforts Falter

Angela Hart

California’s vaccination rates have stagnated, particularly in Black and Latino inner-city neighborhoods and in rural towns. County health officials, who say trust is their most important commodity, need more money for one-on-one interactions with holdouts, but the state has instead largely funneled money to advertising firms and tech companies.

Analysis: Why We’ll Likely Never Know Whether a Covid Lab Leak Happened in China

Elisabeth Rosenthal

If international scientific sleuths are hoping to see a lab log or find a whistleblower, that sort of information won’t be revealed. In China today, it is dangerous to say what you know if it challenges the official government narrative.

Though Millions Are at Risk for Diabetes, Medicare Struggles to Expand Prevention Program

Harris Meyer

Medicare has proposed revamping its payment rules to get more people into a diabetes prevention plan that helps them eat better, exercise more and maintain a healthier lifestyle. Out of an estimated 16 million Medicare beneficiaries whose excess weight and other risk factors make them eligible, only 3,600 have participated since 2018.

Sen. Wyden: $3.5T Budget May Have to Trim but It Can Set a Path to ‘Ambitious Goals’

Michael McAuliff

Sen. Ron Wyden (D-Ore.), who is helping to negotiate the health care spending framework for the Democrats' budget plan, said lawmakers may have to settle for very basic versions of programs deployed in the package. But the key, he added, is to get the "architecture of these changes, bold changes," started and show people what is possible.

Biden’s July Executive Order Includes Drug Pricing Provisions. But Will They Do Enough?

Victoria Knight

The July 9 directive addresses the importation of prescription drugs and broader efforts to reduce the high cost of medicines.

Journalists’ Topics Range From Rural Pharmacy Deserts to Opioid Overdoses

KHN and California Healthline staff made the rounds on national and local media this week to discuss their stories. Here’s a collection of their appearances.

KHN’s ‘What the Health?’: Here Comes Reconciliation

Democrats in Congress reached a tentative agreement to press ahead on a partisan bill that would dramatically expand health benefits for people on Medicare, those who buy their own insurance and individuals who have been shut out of coverage in states that didn’t expand Medicaid. Meanwhile, controversy continues to rage over whether vaccinated Americans will need a booster to protect against covid-19 variants, and who will pay for a new drug to treat Alzheimer’s disease. Rachel Cohrs of Stat and Sarah Karlin-Smith of the Pink Sheet join KHN’s Julie Rovner to discuss these issues and more. Also, Rovner interviews KHN’s Rae Ellen Bichell, who reported and wrote the latest KHN-NPR “Bill of the Month” episode about a mother and daughter who fought an enormous emergency room bill.

Senate Democrats’ Plan Boosts Spending on Medicare, ACA Subsidies, Long-Term Care

Michael McAuliff

The plan from high-wire negotiations would affect five key areas of health, but there will be further tense negotiations among Democratic lawmakers about specifics of the $3.5 trillion in funding. And all Senate Democrats will need to be behind the plan, because Republicans oppose it.

How ERs Fail Patients With Addiction: One Patient’s Tragic Death

Aneri Pattani

Two intractable failings of the U.S. health care system — addiction treatment and medical costs — come to a head in the ER, where patients desperate for addiction treatment arrive, only to find the facility may not be equipped to deal with substance use or, if they are, treatment is prohibitively expensive.

Dying Patients With Rare Diseases Struggle to Get Experimental Therapies

Christina Bennett

When patients with common terminal illnesses such as cancer seek permission for compassionate use of therapies in the testing stage, their requests often are approved. But those with more unusual illnesses say drug companies are rarely willing to provide access.

KHN’s ‘What the Health?’: Becerra Urges Congress to Expand Medicare, Address Rx Prices

Health and Human Services Secretary Xavier Becerra is the special guest for this bonus episode of KHN’s “What the Health?” podcast. He and host Julie Rovner discuss a breadth of topics the secretary oversees, including covid-19, prescription drug prices, Medicare, Medicaid and the Affordable Care Act.

As Congress Wrestles With Plans to Expand Medicare, Becerra Says Any One Will Do

Julie Rovner

In an interview for KHN’s “What the Health?” podcast, HHS Secretary Xavier Becerra says the administration is eager for Congress to make changes to Medicare that will provide more benefits and make more older adults eligible for the program. He also said a priority will be making permanent the enhanced premium subsidies for Affordable Care Act marketplace plans.

Government Oversight of Covid Air Cleaners Leaves Gaping Holes

Lauren Weber and Christina Jewett

Thousands of schools have spent millions of federal covid relief dollars snapping up air cleaning technology that claims to inactivate covid-19. But the devices fall into a regulatory gap.

Why We May Never Know Whether the $56,000-a-Year Alzheimer’s Drug Actually Works

Elisabeth Rosenthal

It could take years for follow-up studies to prove Aduhelm slows the disease — or doesn’t. Meanwhile, its maker will profit.

Paying Billions for Controversial Alzheimer’s Drug? How About Funding This Instead?

Judith Graham

Aduhelm, approved by the Food and Drug Administration last month despite questions about its efficacy, could be prescribed to at least 1 million patients a year, for a price tag of about $56 billion. Experts suggest there might be better ways to spend that money.

Doctors Weigh Pros and Cons of Prescribing Hot-Button Alzheimer’s Drug

Judith Graham

The potential benefits of Aduhelm are small, its effectiveness is not certain, and even the FDA Thursday shifted its guidance on who should get the drug. But physicians are dealing with an onslaught of interest from patients and their families, and figuring out which patients are best positioned to be helped by the drug will be difficult.

Drugmakers’ Spending on Stock, Dividends and Executive Pay Exceeds Research, Democrats Say

Michael McAuliff

The pharmaceutical industry argues that large profits are needed to fund extensive research and innovation. But Democrats on the House Oversight and Reform Committee, seeking to bolster their effort to let Medicare negotiate drug prices, say major drug companies plow more of their billions in earnings back into propping up their stock and enriching executives and shareholders.

California Lawmakers Push Feds to Allow a Therapy That Pays Meth Users to Abstain

Mark Kreidler

The approach, known as contingency management, has helped thousands of veterans kick the methedrine habit, but a federal government ruling has limited its use. California hopes to challenge that and make the treatment a Medi-Cal benefit.

How One Rural Town Without a Pharmacy Is Crowdsourcing to Get Meds

Markian Hawryluk

As more independently owned community pharmacies close, a Colorado town is crowdsourcing ways of getting prescription medicines delivered to those who can’t travel the long distance to the closest pharmacy. But even those stopgap measures don’t always work.

States Step Up Push to Regulate Pharmacy Drug Brokers

Katheryn Houghton

In an ongoing effort to control prescription drug costs, states are targeting the companies that mediate deals among drug manufacturers, health insurers and pharmacies. The pharmacy benefit managers say they negotiate lower prices for patients, yet the nitty-gritty occurs largely behind a curtain that lawmakers are trying to pull back.

KHN’s ‘What the Health?’: Un-Trumping the ACA

The Biden administration is moving to undo many of the changes the Trump administration made to the enrollment process for the Affordable Care Act to encourage more people to sign up for health insurance. Meanwhile, Congress is opening investigations into the controversial approval by the Food and Drug Administration of an expensive drug that might (or might not) slow the progression of Alzheimer’s disease. Joanne Kenen of Politico, Kimberly Leonard of Insider and Sarah Karlin-Smith of the Pink Sheet join KHN’s Julie Rovner to discuss these issues and more. Also, Rovner interviews Marshall Allen of ProPublica about his new book, “Never Pay the First Bill: And Other Ways to Fight the Health Care System and Win.”

KHN’s ‘What the Health?’: How to Expand Health Coverage

Democrats in Congress and the states are devising strategies to expand health coverage — through the Affordable Care Act, Medicare, Medicaid and a “public option.” But progress remains halting, at best. Meanwhile, lawmakers in Washington may have to agree on how to control prescription drug prices if they wish to finance their coverage initiatives. Alice Miranda Ollstein of Politico, Tami Luhby of CNN and Shefali Luthra of The 19th join KHN’s Julie Rovner to discuss these issues and more. Also, Rovner interviews Michelle Andrews, who reported and wrote last month’s KHN-NPR “Bill of the Month” episode about a very expensive sleep study.

Doctores explican pros y contras de recetar la nueva droga para el Alzheimer

Judith Graham

Mientras médicos y expertos en políticas de salud debaten los méritos de Aduhelm, el primer fármaco para el Alzheimer aprobado en 18 años, los pacientes simplemente quieren saber: "¿me ayudará?”.

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